Umhlaza wePancreatic
Inkcazo emfutshane:
Umhlaza wepancreatic ngomnye wemidla yomhlaza ebulalayo echaphazela ipancreas, ilungu elingasemva kwesisu. Kwenzeka xa iiseli ezingaqhelekanga kwipancreas ziqala ukukhula ngokungalawulekiyo, zenze ithumba. Amanqanaba okuqala omhlaza wepancreas adla ngokungabangeli zimpawu. Njengoko ithumba likhula, linokubangela iimpawu ezifana nentlungu yesisu, iintlungu zomqolo, ukwehla kobunzima, ukuphelelwa ngumdla wokutya, kunye ne-jaundice. Ezi mpawu zinokubangelwa zezinye iimeko, ngoko ke kubalulekile ukubona ugqirha ukuba ufumana nayiphi na kuzo.
Unyango olusebenzayo lomhlaza we-pancreatic luxhomekeke kwinqanaba lomhlaza kunye nempilo yesigulana iyonke. Utyando lolona nyango luphambili lomhlaza we-pancreatic, kubandakanya utyando lweWhipple kunye notyando lweDistal, kodwa lunokwenzeka kuphela ukuba umhlaza awusasazekanga ngaphaya kwe-pancreas. Okwangoku, ezinye iindlela ezintsha zotyando kunye nezixhobo, ezinje ngotyando olungena emzimbeni, utyando lwerobhothi kunye netekhnoloji yokuprinta ye-3D, nazo zisetyenziswa kakhulu kunyango lomhlaza we-pancreatic ukuphucula impembelelo yotyando kunye nenqanaba lokusinda kwezigulane.
Unyango lwe-chemotherapy kunye nonyango lwe-radiation lungasetyenziswa ukunyanga umhlaza we-pancreatic, nokuba wedwa okanye udityaniswe notyando. Kwiminyaka yakutshanje, amayeza amatsha e-chemotherapy, anjengeNavumab kunye nePaclitaxel, asetyenziswe kakhulu kunyango lomhlaza we-pancreatic, nto leyo enokuphucula kakhulu ukusebenza kwe-chemotherapy kunye nenqanaba lokusinda kwezigulane.
Unyango olujoliswe ekusetyenzisweni kwamayeza ajolise ekujolisweni kwethumba, njenge-epidermal growth factor receptor inhibitors kunye ne-vascular endothelial growth factor receptor inhibitors, ukuthintela ukukhula nokusasazeka kwethumba. Unyango olujoliswe ekusetyenzisweni lunokuphucula kakhulu ukusebenza kakuhle kunye nezinga lokusinda kwezigulane ezinomhlaza wepancreatic.
Unyango lwe-immunotherapy lubhekisa ekusebenziseni amandla omzimba wesigulana ukuhlasela iiseli zomhlaza, ezifana nezithinteli zokujonga amajoni omzimba, unyango lweeseli ze-CAR-T njalo njalo. Unyango lwe-immunotherapy lunokuphucula amajoni omzimba ezigulana, luphucule ukusebenza kakuhle komhlaza we-pancreatic kunye nezinga lokusinda kwezigulana.
Umhlaza wepancreatic sisifo esibi kakhulu esinokubangela iimpawu ezinzima kwaye kunokuba nzima ukunyanga. Kubalulekile ukubona ugqirha ukuba ufumana naziphi na iimpawu, njengoko ukubonwa kwangoko kunokuphucula amathuba onyango oluphumelelayo.