I-Hyperthermia isebenzisa imithombo eyahlukeneyo yokufudumeza (i-radio frequency, i-microwave, i-ultrasound, i-laser, njl.njl.) ukunyusa ubushushu bezicubu zethumba ukuya kubushushu obusebenzayo bonyango, okubangela ukufa kweeseli zethumba ngaphandle kokonakalisa iiseli eziqhelekileyo. I-Hyperthermia ayinakutshabalalisa iiseli zethumba kuphela, kodwa ikwatshabalalisa nendawo yokukhula nokuzala kweeseli zethumba.
Indlela yeHyperthermia
Iiseli zomhlaza, njengazo naziphi na ezinye iiseli, zifumana igazi ngemithambo yegazi ukuze ziphile.
Nangona kunjalo, iiseli zomhlaza azikwazi ukulawula ubungakanani begazi elihamba kwimithambo yegazi, eliye latshintshwa ngenkani yizo. I-Hyperthermia, indlela yonyango, isebenzisa obu buthathaka bezicubu zomhlaza.
1. I-Hyperthermia lunyango lwesihlanu lwe-tumor emva kotyando, unyango ngemitha, i-chemotherapy kunye ne-biotherapy.
2. Yenye yezona ndlela zibalulekileyo zonyango lwe-adjuvant kwi-tumor (ingadityaniswa neentlobo ngeentlobo zonyango ukuphucula unyango olupheleleyo lwe-tumor).
3. Ayinatyhefu, ayinantlungu, ikhuselekile kwaye ayingenisi ntsholongwane, ikwaziwa ngokuba lunyango oluluhlaza.
4. Idatha yonyango lweklinikhi yeminyaka emininzi ibonisa ukuba unyango luyasebenza, alungenisi ntsholongwane, luyachacha ngokukhawuleza, lunengozi ephantsi, kwaye lubiza kancinci kwizigulana nakwiintsapho (isiseko senkathalelo yasemini).
5. Zonke iithumba zabantu ngaphandle kweethumba zobuchopho nezamehlo zinokunyangwa (zodwa, okanye zidityaniswe notyando, unyango ngemitha, i-chemotherapy, i-stem cell, njl.njl.).
I-tumor cytoskeleton——ikhokelela ngokuthe ngqo kumonakalo we-cytoskeleton.
Iiseli zethumba——zitshintsha indlela i-membrane yeseli evuleka ngayo, zenze kube lula ukungena kwamayeza e-chemotherapy, kwaye zifezekisa isiphumo sokunciphisa ubuthi kunye nokwandisa ukusebenza kakuhle.
I-nucleus ephakathi.
Ukuthintelwa kwe-DNA kunye ne-RNA polymerization yomonakalo obangelwa kukukhula kunye nokubonakaliswa kweemveliso zeeproteni ze-chromosome ezibopha kwi-DNA kunye nokuthintelwa kokwenziwa kweproteni.
Imithambo yegazi yethumba
Nqanda ukubonakaliswa kwe-tumor-derived vascular endothelial growth factor kunye neemveliso zayo
