Umhlaza wePancreatic
Inkcazelo emfutshane:
Umhlaza wePancreatic ngowona mhlaza ubulalayo ochaphazela i-pancreas, ilungu elibekwe emva kwesisu.Kwenzeka xa iiseli ezingaqhelekanga kwi-pancreas ziqala ukukhula ngaphandle kolawulo, zenza ithumba.Amanqanaba okuqala omhlaza we-pancreatic ngokuqhelekileyo awabangeli naziphi na iimpawu.Njengoko i-tumor ikhula, inokubangela iimpawu ezinjengeentlungu zesisu, iintlungu zangasemva, ukunciphisa umzimba, ukulahlekelwa ngumdla wokutya, kunye ne-jaundice.Ezi mpawu zinokubangelwa zezinye iimeko ngokunjalo, ngoko ke kubalulekile ukubonana nogqirha ukuba ufumana naziphi na kuzo.
Olona nyango lusebenzayo lomhlaza we-pancreatic luxhomekeke kwinqanaba lomhlaza kunye nempilo yonke yesigulane.Utyando lolona nyango luphambili kumhlaza wepancreatic, kubandakanya uqhaqho lweWhipple kunye noqhaqho lweDistal, kodwa kunokwenzeka kuphela ukuba umhlaza awunwenwanga ngaphaya kwe-pancreas.Okwangoku, ezinye iindlela ezintsha zotyando kunye nezixhobo, ezinjengotyando oluncinci, utyando lwerobhothi kunye netekhnoloji yoshicilelo lwe-3D, zikwasetyenziswa ngokubanzi kunyango lomhlaza wepancreatic ukuphucula isiphumo sotyando kunye nezinga lokusinda kwezigulana.
Unyango lweChemotherapy kunye nonyango ngemitha lusenokusetyenziswa ukunyanga umhlaza wepancreatic, nokuba uwedwa okanye kudityaniswe notyando.Kwiminyaka yakutshanje, amachiza amatsha e-chemotherapeutic, afana ne-Navumab kunye ne-Paclitaxel, asetyenziswe ngokubanzi kunyango lomhlaza we-pancreatic, onokuphucula kakhulu ukusebenza kwe-chemotherapy kunye nezinga lokusinda kwezigulana.
Unyango olujoliswe kuyo lubhekiselele ekusetyenzisweni kweziyobisi ezijolise kwiithagethi zethumba, ezifana ne-epidermal growth factor receptor inhibitors kunye ne-vascular endothelial growth factor receptor inhibitors, ukuthintela ukukhula kwethumba kunye nokusasazeka.Unyango olujoliswe kuyo lunokuphucula kakhulu ukusebenza kunye nesantya sokusinda kwezigulane ezinomhlaza we-pancreatic.
I-Immunotherapy ibhekisela ekusebenziseni amandla omzimba wesigulana ukuhlasela iiseli zomhlaza, ezifana ne-immune checkpoint inhibitors, unyango lweseli ye-CAR-T njalo njalo.Unyango lwe-Immunotherapy lunokonyusa ukhuseleko lwezigulana, luphucule ukusebenza komhlaza wepancreatic kunye nenqanaba lokusinda kwezigulana.
Umhlaza wePancreatic sisifo esiyingozi esinokubangela iimpawu ezinzima kwaye kunokuba nzima ukunyanga.Kubalulekile ukubonana nogqirha ukuba ufumana naziphi na iimpawu, njengoko ukufumanisa kwangoko kunokuphucula amathuba onyango oluyimpumelelo.