Unyango lwesihlanu lweeTumors - Hyperthermia
Xa kufikwa kunyango lwethumba, abantu bahlala becinga ngotyando, ichemotherapy, kunye nonyango lweradiation.Nangona kunjalo, kubaguli abanomhlaza abakwinqanaba eliphezulu abaphulukene nethuba lotyando okanye aboyika ukunganyamezeli ngokwasemzimbeni ichemotherapy okanye iinkxalabo malunga nokusasazeka kwemitha yonyango lwemitha, ukhetho lwabo lonyango kunye nexesha lokusinda linokuba ngumda.
I-Hyperthermia, ukongeza ekusetyenzisweni njengonyango oluzimeleyo lwamathumba, inokudityaniswa nechemotherapy, unyango lweradiation, iyeza lemveli laseTshayina, kunye nolunye unyango ukwenza ukuhambelana kwezinto eziphilayo.Yonyusa ubuntununtunu bezigulana kwi-chemotherapy, unyango lwemitha, kunye namayeza emveli aseTshayina, okukhokelela ekuphelisweni okusebenzayo kweeseli zethumba eliyingozi.I-Hyperthermia iphucula umgangatho wobomi kwaye yandisa ubomi bezigulane ngelixa inciphisa imiphumo emibi ebangelwa unyango lwe-radiation kunye ne-chemotherapy.Ngoko ke, ibizwa ngokuba"unyango oluluhlaza"luluntu lwezonyango lwamazwe ngamazwe.
I-RF8 Hyperthermia System ene-Ultra-High-Speed Electromagnetic Waves
THERMOTRON-RF8yinkqubo ye-tumor hyperthermia ephuhliswe ngokudibeneyo yi-Japan National Institute of Science and Technology, i-Kyoto University School of Medicine, kunye ne-Yamamoto VINITA Corporation.
*RF-8 ineminyaka engaphezu kwama-30 yamava ezonyango.
*Isebenzisa itekhnoloji ye-8MHz yombane yombane ekhethekileyo yehlabathi.
*Inkqubo yayo yokulawula ubushushu obuchanekileyo inomda wempazamo ongaphantsi kuka +(-) 0.1 degrees celcius.
Le nkqubo ilawula ngokufanelekileyo imitha ye-electromagnetic wave ngaphandle kokufuna ukukhuselwa kombane.
Isebenzisa uyilo olululo oluncediswa yikhompyuter ukucwangciswa konyango kunye nokubeka iliso ngexesha lenkqubo yonyango.
Iimpawu zeHyperthermia:
Intloko neNtamo, Amalungu:Amathumba entloko kunye nentamo, amathumba amathambo anobungozi, izicubu ezithambileyo.
Umngxuma weThoracic:Umhlaza wemiphunga, umhlaza wommizo, umhlaza wamabele, i-mesothelioma eyingozi, i-lymphoma eyingozi.
Umngxunya wePelvic:Umhlaza wezintso, umhlaza wesinyi, umhlaza wesinyi, umhlaza wamatyhalarha, umhlaza welungu lobufazi, umhlaza womlomo wesibeleko, umhlaza we-endometrial, umhlaza wesibeleko.
Umngxuma Wesisu:Umhlaza wesibindi, umhlaza wesisu, umhlaza wepancreatic, umhlaza wesisu.
Izinto eziluncedo zeHyperthermia edityaniswe nolunye unyango:
I-Hyperthermia:Ngokufudumeza izicubu ezinzulu kwindawo ekujoliswe kuyo ukuya kuma-43 degrees Celsius, iprotein denaturation iyenzeka kwiiseli zomhlaza.Unyango oluninzi lunokukhokelela kwi-apoptosis yeseli yomhlaza kunye nokuguqula imeko yendawo yethishu kunye nemetabolism, okukhokelela ekwandeni kwemveliso yeeproteni ezothusayo zobushushu kunye ne-cytokines, ngaloo ndlela kukhulisa ukusebenza komzimba.
Hyperthermia + Chemotherapy (Intravenous):Ukusebenzisa isinye kwisithathu ukuya kwisiqingatha sedosi ye-chemotherapy eqhelekileyo, ukulawulwa kwe-intravenous synchronized kwenziwa xa ubushushu bomzimba obunzulu bufikelela kuma-43 degrees Celsius.Oku kwandisa ugxininiso lwamachiza kunye nokusebenza kakuhle ngelixa kuncitshiswa iziphumo ebezingalindelekanga zechemotherapy.Inokuzanywa njengokhetho “lokuncitshiswa kwetyhefu” yechemotherapy kwizigulana ezingayilungelanga ichemotherapy yesiko ngenxa yeemeko zabo zomzimba.
I-Hyperthermia + Ukutyholwa (Ukuphuma kweThoracic kunye neSisu):Ukunyanga i-pleural enxulumene nomhlaza kunye ne-peritoneal effusions kulucelomngeni.Ngokuqhuba ngaxeshanye i-hyperthermia kunye ne-perfusing chemotherapeutic agents ngokusebenzisa iityhubhu zokuhambisa amanzi, iiseli zomhlaza zinokutshatyalaliswa, ukunciphisa ukuqokelelwa kwamanzi kunye nokunciphisa iimpawu zesigulane.
Unyango lweHyperthermia + neRadiation Therapy:Unyango ngemitha alusebenzi kangako kwiiseli zesigaba S, kodwa ezi seli zinovelwano kubushushu.Ngokudibanisa i-hyperthermia kwiiyure ezine ngaphambi okanye emva konyango lwemitha, unyango lunokuqinisekiswa kuzo zonke iiseli kwizigaba ezahlukeneyo zomjikelo weseli kwangolo suku lunye, okukhokelela ekunciphiseni okunokubakho kwe-1/6 kwidosi yemitha.
Imigaqo kunye nemvelaphi ye-Hyperthermia Treatment
Igama elithi “Hyperthermia” lisuka kwigama lesiGrike elithetha “ubushushu obugqithiseleyo” okanye “ubushushu obugqithiseleyo.”Ibhekisela kwindlela yonyango apho imithombo yobushushu eyahlukeneyo (i-radiofrequency, i-microwave, i-ultrasound, i-laser, njl.) isetyenziselwa ukunyusa ubushushu bezicubu zethumba ukuya kwinqanaba lonyango elisebenzayo, elibangela ukufa kweseli yethumba ngelixa usindisa iiseli eziqhelekileyo kumonakalo.I-Hyperthermia ayibulali kuphela iiseli zethumba kodwa iphinda iphazamise ukukhula kunye nokuzala kweeseli zethumba.
Umseki we-hyperthermia unokulandelwa emva kwi-Hippocrates kwiminyaka engama-2500 eyadlulayo.Ngophuhliso olude, iimeko ezininzi ziye zabhalwa kumayeza anamhlanje apho amathumba anyamalalayo emva kokuba abaguli bafumana umkhuhlane ophezulu.Kwi-1975, kwi-International Symposium kwi-Hyperthermia eyayibanjelwe eWashington, DC, i-hyperthermia yaqatshelwa njengendlela yesihlanu yonyango lwamathumba anobungozi.Yafumana isatifikethi se-FDA kwi-1985.Ngo-2009, iSebe lezeMpilo laseTshayina lakhupha "Inkcazo yoLawulo lwe-Local Tumor Hyperthermia kunye neTechnologies eNtsha," iqinisa i-hyperthermia njengenye yeendlela ezibalulekileyo kunyango olubanzi lomhlaza, kunye notyando, unyango lweradiation, ichemotherapy, kunye ne-immunotherapy.
Uphononongo lwetyala
Ityala le-1: Isigulane esine-metastasis yesibindi esivela kwi-renal cell carcinomawafumana i-immunotherapy iminyaka eyi-2 kwaye wafumana iiseshoni ezidibeneyo ze-55 ze-hyperthermia.Okwangoku, umfanekiso ubonisa ukunyamalala kwamathumba, abamakishi be-tumor baye bancipha ukuya kumanqanaba aqhelekileyo, kwaye ubunzima besigulane bunyuke ukusuka kwiipounds ezili-110 ukuya kwi-145 pounds.Banokuphila ubomi obuqhelekileyo ngokwentelekiso.
Ityala le-2: Isigulane esine-pulmonary mucinous adenocarcinomanamava okuqhubela phambili kwesifo emva kotyando, unyango lweradiation, unyango ekujoliswe kulo, kunye nonyango lwamajoni omzimba.Umhlaza wawune-metastasis exhaphakileyo kunye ne-pleural effusion.Ukonyuka konyango lwe-ion olukhawulezayo oludityaniswe nonyango oluphezulu lwe-immunotherapy lwaqalwa kwiiveki ezintathu ezidlulileyo.Unyango aluzange lubonise imiphumo emibi, kwaye isigulane asinakho ukuphazamiseka okubalulekileyo.Olu nyango lubonisa ithuba lokugqibela lesigulana.
Ityala le-3: Isigulana somhlaza we-Postoperative colorectaloye kwafuneka ayeke unyango olujoliswe kuyo ngenxa yomonakalo omkhulu wolusu.Emva kokugqiba iseshoni enye yonyango lwe-ion olukhawulezayo, isigulane safumana i-11iipounds ubunzima.
Ixesha lokuposa: Aug-04-2023