Apha ePuhua, ubuchwepheshe obuphambili bonyango lomhlaza budibene nonyango lwendalo ukukunceda ukulwa nesifo kwaye ugcine umgangatho wobomi bakho.
Unyango olunezifundo ezahlukeneyo lomhlaza
Unyango lomhlaza
Isibhedlele samazwe ngamazwe saseBeijing ePuhua sisebenzisa ubuchwepheshe obuphambili ukunyanga umhlaza ngamandla. Apha ePuhua, ubuchwepheshe obuphambili bonyango lomhlaza budityaniswa nonyango lwendalo ukukunceda ukulwa nesifo nokugcina umgangatho wobomi bakho.
Injongo kaPuhua:
·Iqela leengcali ezisebenzisa iinkalo ezahlukeneyo
·Isicwangciso sonyango esilungiselelwe wena, esipheleleyo
·Iindlela zonyango olusebenzayo ukuze luhambelane nenqanaba lesimila
·Nciphisa iziphumo ebezingalindelekanga
·Ukuphucula umgangatho wobomi besigulane ngokubanzi
Iindlela zonyango ezifumaneka ePuhua
Ukususwa kweRadiofrequency
Ngokusebenzisa iteknoloji ye-Ultrasound kunye ne-CT, siyakwazi ukufaka ngqo iinaliti ezivelisa ubushushu embindini wendawo yomhlaza. Emva koko indawo iyafudunyezwa kwaye xa idlula i-60℃, ukuqhekeka okucwangcisiweyo kweeproteni kwiiseli zomhlaza kuya kwenzeka ukuwohloka kude kube kwinqanaba lokuba zingabi nabungozi.
Ukususwa kweCryosurgical (CSA)
Kusetyenziswa iindlela ezikhokelwa kukwenza imifanekiso (i-Ultrasound, i-CT okanye i-MRI), ii-cryo-probes zifakwa kwiithumba ukuze kuncitshiswe ubushushu bendawo ekujoliswe kuyo -160℃ okanye ngaphantsi. Kamva ubushushu buphakanyiswa phakathi kwama-20 ukuya kuma-40℃. Le nkqubo iphindaphindwa kabini okanye kathathu, nto leyo ekhokelela ekususweni ngokupheleleyo kwethumba.
I-CSA inezi nzuzo zilandelayo:
• Isebenza kuzo zombini iithumba ezincinci nezinkulu. Ingasetyenziselwa ukuphelisa iithumba ezinde okanye ezininzi.
• Ukususwa kwemithambo yegazi ebuhlungu akuyi kubangela umonakalo kwimithambo yegazi emikhulu kunye ne-trachea, ngoko ke ingasetyenziselwa ukunyanga iithumba ezikufutshane nezo ndawo.
• Lutyando olungenazintlungu, kwaye lunceda ekunciphiseni iintlungu ezibangelwa ngumhlaza.
• Yonke inkqubo yokususwa kwesisu nge-cryosurgical ingajongwa ngeendlela zokwenza imifanekiso ezifana ne-ultrasound, i-CT okanye i-MRI.
• Emva kokuba iiseli zomhlaza zitshatyalalisiwe yi-CSA, iiseli zomhlaza ezifileyo ziya kukhupha ii-antigens eziya kukhuthaza inkqubo yomzimba yokuzikhusela ukuba itshabalalise naziphi na iiseli zomhlaza eziseleyo kwaye inciphise ukuphinda ubuye komhlaza.
Ungenelelo lweMithamo yeCancer (CMI)
Ngokufaka i-catheter kwimithambo yegazi ekujoliswe kuyo kunye nokufaka i-embolic material, ii-chemotherapy agents okanye amayeza emveli aseTshayina sinokubangela ukulahleka kwegazi kwiiseli zomhlaza nto leyo ekhokelela kwi-ischemia necrosis yezicubu zethumba. Ngokwenza oku siyakwazi ukubulala umhlaza ngendlala size siwubulale.
Unyango lweNanoKnife
Ikwaziwa ngokuba yi-Irreversible Electroporation (IRE). Ingqiqo yayo ihamba ngolu hlobo lulandelayo: ngexesha lenkqubo, kunikwa amandla aphezulu ombane kunye nee-pulses ezimfutshane kakhulu ukutshabalalisa isakhiwo se-lipid bilayer ye-cancer cell membrane kunye nokwenza ii-nano-size pores ezininzi ezingenakujikwa kwi-cell membrane. Ukungena kwe-cell membrane kuya kutshintshwa ukuvumela iimolekyuli zobukhulu obahlukeneyo ukufikelela ngokukhululekileyo kwiiseli, nto leyo eya kukhokelela ekufeni kweseli.
Unyango lweNanoknife lungasetyenziswa ukunyanga iithumba kwizitho eziqinileyo ezifana nepancreas, isibindi, imiphunga, izintso kunye neprostate, kwaye lufanelekile ngakumbi kwiithumba ezikufutshane nepancreas, ummandla we-hepatic hilar, i-gallbladder, i-bile duct kunye ne-ureters.
Unyango lwePhotodynamic (PDT)
(ngamanye amaxesha ibizwa ngokuba yi-photo-chemotherapy), luhlobo lwe-phototherapy olusebenzisa iikhompawundi ezingenabungozi ekukhanyeni ezivezwa kubude bokukhanya obukhethiweyo, apho zisebenza kwaye zibe yityhefu kwizicubu ezinobungozi ezijoliswe kuzo nakwezinye izicwili ezijoliswe kuzo. I-PDT ibonakalisiwe ukuba iyabulala iintsholongwane, iifungi kunye neentsholongwane, kwaye isetyenziswa kakhulu ekunyangeni i-acne. Isetyenziswa ngokwezonyango ukunyanga uluhlu olubanzi lweemeko zonyango, kubandakanya i-wet age-related macular degeneration (AMD) kunye nomhlaza onobungozi, kwaye ibonwa njengecebo lonyango elisebenzayo nelikhethayo elingenabungozi kangako kwaye lingabi yityhefu kangako.
Unyango lwe-Immunotherapy (unyango lwe-DC-CIK)
Unyango lwe-CIK (iiseli zokubulala ezibangelwa yi-cytokine): Iiseli ze-CIK ziiseli ze-T ezinobuthi ezinokufuna nokubulala iiseli zethumba. Inani leeseli ze-CIK ezikhoyo emzimbeni lincinci kakhulu, kwaye alanelanga ukulwa nomhlaza. Kunyango lwe-CIK, iiseli ze-CIK ziyahlukaniswa, zandiswe ubuncinane izihlandlo ezili-1,000, zize ziphinde zibuyiselwe emzimbeni wesigulana.
I-Hyperthermia:
Uvavanyo lubonisa ukuba amandla okupholisa eeseli zethumba aphantsi kakhulu kunalawo eeseli eziqhelekileyo. Xa ubushushu bufikelela kwi-42.5 ℃ kwaye buhlala imizuzu engaphezu kwama-30, iiseli zethumba ziya kufudumala ngokukhawuleza zize zibangele ukwenzakala, ukubola kunye ne-necrosis. Nangona kunjalo, iiseli eziphilileyo zinokuphepha umonakalo ngokusebenzisa indlela elungileyo yokupholisa. I-Thermotron-RF8 ngumatshini wamva nje we-hyperthermia ophuhliswe eJapan, onokubeka ithumba ngokuchanekileyo kwaye wenze i-hyperthermia. Nangona inciphisa umthamo wethumba kwaye inciphise iintlungu, inokuthintela ukuphinda komhlaza kwaye iphucule iziphumo zezinye iindlela zonyango.
Unyango lwe-Immunotherapy lwe-PD-1:
I-PD-1/PD-L1: I-PD-1 luhlobo olunye lwe-receptor yeseli ye-T esebenzayo. Indawo engaphakathi yethumba iya kubangela imolekyuli ye-PD-1 yeseli ye-T engenileyo, iseli yethumba iya kuveza ii-ligands ze-PD-1 (PD-L1 kunye ne-PD-L2), ezikhokela indlela ye-PD-1 ziqhubeke nokusebenza kwindawo encinci yethumba. Emva kokuba i-PD-L1 idibene ne-PD-1, umsebenzi weseli ye-T uya kuthintelwa, kwaye awukwazi ukuthumela imiqondiso ehlasela ithumba kwinkqubo yomzimba yokuzikhusela. I-PD-1/ PD-L1 inhibitor inokuthintela uqhagamshelo lwe-PD-1 kunye ne-PD-L1, kwaye ithintele imiqondiso yokulawula engalunganga ukubuyisela amandla okuphila eseli ye-T, kwaye emva koko iphucule impendulo yomzimba. I-PD-1 kunye ne-PD-L1 inhibitor zinefuthe elikhulu kwiindlela ezahlukeneyo zonyango lomhlaza.
Amayeza eMveli aseTshayina (i-TCM)
I-TCM yindlela yonyango ekhuselekileyo nesebenzayo exhasayo esetyenziswa kunye nezinye iindlela zonyango. Iimifuno ezininzi zaseTshayina zineziphumo ezinamandla zokuphucula amasosha omzimba, kwaye zombini zinokunyusa iziphumo ze-chemotherapy, unyango lwe-radiation, utyando, kunye nezinye iindlela ngelixa zinciphisa ubuthi kunye neziphumo ebezingalindelekanga. Iimifuno zesintu zaseTshayina zinokunikwa ngomlomo, nge-IV infusion, okanye zifakwe kwimithambo yokondla ithumba ngoncedo lwe-DSA (digital subtraction angiography)
isikhokelo.
Iqela lezonyango leMicimbi emininzi
UGqr. Xue Zhongqi—uMlawuli we-Oncology, uGqirha oyiNtloko we-Oncology
UDkt. Xue uzisa eBeijing Puhua International Hospital iziphumo zeminyaka engaphezu kwamashumi amathathu (30) yamava ezonyango njengomnye woogqirha abaphambili bomhlaza eTshayina. Ungugqirha okhokelayo negunya ekuxilongeni nasekunyangeni iintlobo ezahlukeneyo zomhlaza. Uyaziwa ngomsebenzi wakhe kumhlaza webele, ingakumbi kwicandelo lokususwa kwebele kunye nokwakhiwa kwakhona kwamabele.
UDkt. Xue wenze uphando olunzulu kunye nophando lwezonyango kwiindawo ezifana nomhlaza we-colorectal, i-sarcoma, umhlaza wesibindi kunye nomhlaza wezintso, kwaye upapashe amaphepha emfundo kunye namanqaku angaphezulu kwamashumi amabini (20) (zombini uphando olusisiseko kunye nolwezonyango) kwezi ndawo zonyango. Uninzi lwezi ncwadi zifumene amabhaso ahlukeneyo afanelekileyo.
UGqr. Zhao Yuliang—uMlawuli oManyeneyo we-Oncology, iNgcali ePhambili ye-Oncology
UDkt. Zhao unamava akhethekileyo, uqeqesho kunye nolwazi malunga nolawulo lwezonyango lwezigulane ze-oncology kunye nolawulo lwezonyango kunye nonyango lweemeko zomhlaza ezinzima.
UDkt. Zhao unobuchule obukhulu ekunciphiseni iziphumo ebezingalindelekanga ezinokubakho kwisigulane ngenxa yechemotherapy. Ezama rhoqo ukuphucula izinto ezilungileyo kunye nentuthuzelo yezigulane zechemotherapy, ngelixa kwangaxeshanye ezama ukuphucula umgangatho wobomi bazo, uDkt. Zhao uye waba ngummeli ophambili wokuphuhlisa isicwangciso sonyango esibanzi nesigxile kwisigulana ngasinye somhlaza wesigulane ngasinye.
UGqr. Zhao usebenza kwinkqubo ye-integrated oncology kwiBeijing Puhua International Hospital, apho asebenza khona ngokubambisana ne-oncology yotyando, amayeza emveli aseTshayina, kunye nonyango lokuzikhusela kwizifo zeseli ukuze kuphuculwe iziphumo zonyango zesigulana ngasinye.
UGqr. Allen (Yuansen) Gao
UGqr. Allen Gao ngugqirha we-TCM ophumelele kwiYunivesithi yaseLiaoning yezonyango zemveli zaseTshayina. Wafunda phantsi koNjingalwazi uLigong Xue owaziwa ngophando lwakhe lwezifo ze-meridian-tendon kwi-Acupuncture Institute of the Chinese Academy of Sciences kunye neLondon Application Technology Research Institute. Usebenzise uphando lweklinikhi lwe-meridian-tendon kakhulu, kwaye unamava ophando olunzulu kunye nonyango kwiindlela kunye nokunyanga iintlungu, kunye nezifo zemisipha. Ukwanawo namava amaninzi eklinikhi okusebenzisa i-acupuncture kwiintlobo ezininzi zezifo ze-neurological, i-intervertebral disc herniation, isifo seswekile kunye neentlungu ezingapheliyo. UGqr. Allen Gao usebenzisa ubuchule be-TCM kwaye uzidibanisa namayeza kunye neendlela zanamhlanje zaseNtshona. Unegama elihle kakhulu kunyango lwezifo ze-neurological kunye ne-spinal.