I-HIFU esanda kuqaliswa i-non-invasive-ultrasound ablation kwisibhedlele saseBeijing Puhua International (BPIH) ineenzuzo ezibalulekileyo kwiinkqubo ezisetyenziswa ngokuqhelekileyo ekunyangeni umhlaza wepancreatic.
Umhlaza wePancreatic kunye ne-High Intensity Focused Ultrasound Ablation (HIFU)
Umhlaza wePancreatic
Ukuxilongwa kwangaphambili komhlaza we-pancreatic kunzima kakhulu.Ngumhlaza oyingozi kakhulu odla ngokuba noxinzelelo olubi.I-National Institutes of Health ibika ukuba i-1 iminyaka yokuphila komhlaza we-pancreatic yi-8% kuphela, i-5-year-survival rate ingaphantsi kwe-5%, kwaye umyinge wokulindela ubomi yi-2 ukuya kwiinyanga ezi-3.Uninzi lwezigulana zivame ukuxilongwa kuphela kwinqanaba eliphezulu lesi sifo, njengoko iimpawu zomhlaza we-pancreatic zihlala zibonakala kuphela xa isifo siqhubekile.Iimpawu ziquka intlungu yesisu, ukulahleka kwesisindo esingaqondakaliyo kunye nobunzima bokugaya ukutya okunamafutha.Kwinqanaba eliphezulu iimpawu zentlungu ephantsi yomqolo ichaphazela kakhulu umgangatho wobomi besigulane kwaye ukusetyenziswa kweziyobisi ze-analgesic kunokubonelela ngesiqabu, kodwa ngokuqhelekileyo akwanelanga.
Ngaphezu koko kwinqanaba eliphezulu lesi sifo, ukhetho lotyando alunakwenzeka kwaye kwiimeko ezininzi iindlela zonyango ezisetyenziswa ngokuqhelekileyo kunye ne-chemotherapy zizisa iziphumo ezininzi ezingathandekiyo kunye netyhefu.
I-HIFU esanda kuqaliswa i-non-invasive-ultrasound ablation kwisibhedlele saseBeijing Puhua International (BPIH) ineenzuzo ezibalulekileyo kwiinkqubo ezisetyenziswa ngokuqhelekileyo ekunyangeni umhlaza wepancreatic.
Kwizigulane ezinomhlaza we-pancreatic ekuqaleni, i-HIFU inokusisusa ngokupheleleyo isilonda.Kwizigulane ezinomhlaza we-pancreatic ophakathi okanye ophambili, unyango lwe-HIFU lunokunciphisa ngokukhawuleza iintlungu zesisu kunye neentlungu ezisezantsi ezibangelwa ngumhlaza we-pancreatic.
Yintoni iHIFU?
I-HIFU imfutshane kwi-high-intensity focused ultrasound ablation kwaye imele isizukulwana esilandelayo seunyango olungeyongozi kancinane kumhlaza.
I-HIFU isebenzisa Ukungena kakuhle kwe-ultrasound, kunye nokuqina njengoko i-ultrasound beam ihamba nge-transducer probe kwaye igxininise kwindawo, ijolise ngokuchanekileyo kwi-tumor, eshushu phakathi kwe-60 ukuya kwi-100 ye-Celsius.Iiproteni zeselula ze-tumor coagulate ekhokelela kwi-tumor ablation (ukutshatyalaliswa ngokushushu kweethishu), ngaphandle kokwenzakala kwezicubu ezijikelezileyo.Izicubu zethumba ezifileyo ziphinda zifunxeke ngokuthe ngcembe ngumzimba.
Kwimeko yomhlaza we-pancreatic ongasebenziyo, unyango lwe-HIFU lunokunciphisa ngokufanelekileyo umthwalo wethumba kunye nokunciphisa umdla weentlungu zethumba ngokuchithwa kwezicubu, ukunciphisa ubunzima be-tumor kunye ne-neuromodulation, ngaloo ndlela kwandisa ukusinda kwesigulane kunye nokuphucula umgangatho wobomi.
Ukulandela unyango, i-88% yezigulane zafumana amanqanaba ahlukeneyo okunciphisa intlungu,
ngaphandle kweengxaki ezinzulu ezifana nokopha kwe-gastrointestinal hemorrhage okanye i-gastric-intestinal perforation kunye ne-MRI scans ephuculweyo ityhila ukukhutshwa kwezicubu ezisebenzayo kwindawo yonyango ye-HIFU.
Emva kokwenza uphando kunye nophuhliso olubanzi, unyango lwe-HIFU luye lwamkelwa ngokubanzi kwaye lwakhuthazwa kunyango lomhlaza we-pancreatic.
Ngenxa yokuba ayilulo uhlaselo, utyando kwiimeko ezininzi kufuneka luthintelwe kwaye uninzi lwezigulana lufuna unyango olunye lwe-HIFU ukuphumeza isiphumo esinqwenelekayo sokutshatyalaliswa kwethumba.Okumangalisayo kukuba, emva kosuku olunye lokufumana unyango, uninzi lwezigulana zinokubuyela ekhaya, njengoko kungekho ziphumo zichaphazela impilo yezigulana.
Ukuthelekiswa kwe-HIFU kunye neendlela zonyango eziqhelekileyo
Ngelishwa i-70% - 80% yezigulane zomhlaza we-pancreatic azifunyaniswanga kwinqanaba lokuqala lemeko.Xa ukuxilongwa komhlaza we-pancreatic kwenzeka, isigulane ngokuqhelekileyo sele siqhubele phambili kwinqanaba eliphakathi okanye eliphambili lale meko, kunye nexesha eliqhelekileyo lokuphila kwiinyanga ezi-3-6 kuphela.Emva kokuba ifunyenwe, ngaphantsi kwe-10% yezigulane ezinomhlaza we-pancreatic ngabaviwa abafanelekileyo bokuhlinzwa, okubuhlungu kunye nomngcipheko kwaye ngokuqhelekileyo ukwandisa ubomi besigulane kuphela ukuya kwiinyanga ezili-9.Nokuba kudityaniswe neradiotherapy kunye nechemotherapy, ixesha lokusinda linokwandiswa kuphela ngeenyanga ezi-0.5-1 ezongezelelweyo.Iinketho zonyango eziqhelekileyo zineendleko kwaye azisebenzi, njengoko zingenakukwandisa ixesha lokuphila kwaye zinike isiqabu kwiintlungu kwisigulane.
Nangona kunjalo phantse zonke izigulana zomhlaza wepancreatic zifanelekile kunyango olungelulo, umngcipheko ophantsi we-HIFU.
Ngokwezibalo zethu, ukusinda kwezigulane kunokwandiswa ukusuka kwi-3 ukuya kwiinyanga ze-6 ukuya kwi-1 ukuya kwi-2 iminyaka kunye ne-98% ephawulekayo yezigulane ezifumana ukuphucuka okubonakalayo kwintlungu kunye nokwandiswa kobomi emva kokufumana unyango lwe-HIFU!
Izinto eziluncedo zeHIFU Ultrasound Ablation Therapy
1.Noninvasivetreatment ukugcina amalungu kunye nezakhiwo, ngaphandle gazi kwaye akukho mitha.
2.Imodyuli yokujoliswa kwe-3D ichaza umda we-tumors kwaye ibala isicwangciso sonyango se-3D, ibeka iliso rhoqo kwiimpendulo zezicubu kunye nokulungelelanisa iiparamitha zonyango ngokufanelekileyo, ukufezekisa iprotocol yonyango lomntu ngamnye.
3.Ukukhutshwa ngokusesikweni nangokuchanekileyo.Ngempazamo yokuqokelelwa kwe-plus kunye ne-1mm, intshukumo echanekileyo ye-6-dimensional motion system inokuphelisa amathumba akufuphi nemikhumbi emikhulu okanye imithambo-luvo ngokukhuselekileyo.
4.Kwiimeko ezininzi kuphela iseshoni yonyango enye kuphela efunekayo kwaye akukho mida ngenxa yobukhulu kunye nokumila kwethumba, Umda phakathi kwezicubu ezinyangwayo nezinganyangwanga unokuba mxinwa njenge-6 ukuya kwiiseli ezili-10 ububanzi.
5.Ixesha lokwenyani lombala we-doppler ultrasound-guided the treatment with digital quantitative analysis ivumela ukubeka iliso ngexesha lonyango lonke kwaye ibonelele ngoko nangoko umfanekiso we-ultrasound ukuvavanya umphumo opheleleyo wokulandela unyango.
6.Amandla ommandla ekugxilwe kuwo aphakame ngokwaneleyo ukubangela ubutyhefu bobushushu obukhawulezileyo (iqondo lobushushu elingaphezulu kwe-56Derees Celsius) eliya kubangela i-coagulative necrosis engaguqukiyo.
7.Ukwenza kusebenze amajoni omzimba, njengoko izicubu ze-necrotic zilahlwa yimpendulo yokuphiliswa komzimba.